Catalytic enantioselective conjugate addition of dialkylzinc reagents to N-substituted-2,3-dehydro-4-piperidones.
نویسندگان
چکیده
The first, highly enantioselective, copper/phosphoramidite-catalyzed conjugate addition of dialkylzinc reagents to N-substituted 2,3-dehydro-4-piperidones is described.
منابع مشابه
Phosphoramidites: marvellous ligands in catalytic asymmetric conjugate addition.
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SYNLETT 2006, No. 13, pp 2119–212317.08.2006 Advanced online publication: 09.08.2006 DOI: 10.1055/s-2006-948201; Art ID: G12406ST © Georg Thieme Verlag Stuttgart · New York Abstract: The desymmetrization reaction is a common strategy to synthesize complex chiral molecules. The selective cleavage of carbon–carbon or carbon–heteroatom bonds is well known, whereas the enantioselective cleavage of ...
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ورودعنوان ژورنال:
- Chemical communications
دوره 13 شماره
صفحات -
تاریخ انتشار 2005